Novel Device Targets Dry Eye and Beyond with Thermal Imaging

A groundbreaking innovation in ocular health assessment is on the horizon, as a new University of Waterloo spinoff company, ThermOcular AI, unveils its pioneering approach to eye temperature monitoring.

Transforming Ocular Diagnostics

Founded by vision science and engineering researchers from Waterloo, ThermOcular AI aims to introduce a patented thermal imaging system to the market. This system is designed to meticulously measure the temperature of the cornea, the transparent portion of the eye that covers the iris and pupil. With the potential to revolutionize ocular diagnostics, this novel device could serve as a valuable tool for screening dry eye and potentially other ocular diseases.

The research outlining the development of this innovative technology was recently published in IEEE Access, showcasing the culmination of years of dedicated effort by the team behind ThermOcular AI.

Inspiration and Innovation: Dr. Paul Murphy's Insights

Dr. Paul Murphy, a professor at the School of Optometry & Vision Science and chief scientific officer of ThermOcular AI, explained the inspiration behind the project: "If you have a fever, it's likely an indication of an infection causing inflammation. If you have inflammation in the eye, it can increase blood flow, so we figured temperature might indicate disease in the eye too."

Targeting Dry Eye: Addressing a Prevalent Condition

Dry eye, a prevalent and often debilitating condition, served as a focal point for ThermOcular AI's initial endeavors. The condition encompasses a range of symptoms, from insufficient tear production to compromised tear composition, leading to discomfort and potential vision impairment.

"While most dry eye symptoms can be managed with conventional treatments, severe cases can result in significant complications, including corneal scarring and vision loss," noted Dr. Murphy.

Beyond Diagnosis: Delivering Rapid Assessment

ThermOcular AI's vision extends beyond mere diagnosis; the company aims to deliver a rapid, non-invasive method for assessing ocular health. By capturing a brief video of the patient's eye and analyzing the pattern of ocular surface temperature changes over time, clinicians can swiftly ascertain whether dry eye or other ocular surface diseases are likely present.

Dr. Ehsan Zare Bidaki, postdoctoral fellow and CEO of ThermOcular AI, emphasized the potential impact of their technology: "It would be a quick screening test for patients, compared to other tests that might take an hour. A clinician would still be involved to decide next steps."

Since its inception in January 2024, ThermOcular AI has been on an accelerated trajectory, fueled by collaborations with Waterloo's startup incubator, Velocity. This strategic partnership has provided invaluable support in navigating the transition from research to entrepreneurship, facilitating product-market fit, sales traction, and network expansion.

Envisioning Accessibility: Redefining Ocular Care

Looking ahead, Zare Bidaki envisions ThermOcular AI as a game-changer in accessible ocular care, particularly for patients deterred by the prohibitive costs associated with specialized eye examinations. "This will be a much more affordable method that will lead to their being able to use the specific medication that will help most for their type of disease. I think this company will help people lead healthier lives," he affirmed.

With its innovative approach and commitment to improving patient outcomes, ThermOcular AI is poised to redefine standards of ocular health assessment and pave the way for a more inclusive and effective approach to eye care.

Reference

Ehsan Zare Bidaki et al, A Novel System for Ocular Surface Temperature Measurement and Tracking, IEEE Access (2023). DOI: 10.1109/ACCESS.2023.3341354