Vision in Aging Patients with Diffractive Multifocal IOLs Shows Progressive Declines, Study Finds

Vision in Aging Patients with Diffractive Multifocal IOLs Shows Progressive Declines, Study Finds

January 18, 2022

Patients implanted with diffractive multifocal IOLs experienced significant declines in corrected distance visual acuity (CDVA), distance corrected near VA (DCNVA), and near area of focus (AoF) with aging, according to a recent study.

The study was led by Ryo Terauchi, MD, and associates from the Department of Ophthalmology at the Jikei University School of Medicine in Tokyo, Japan.

The researchers compared the impact of aging in this patient population by dividing patients who received diffractive multifocal IOLs into four groups: those under 50 years of age, 50 to 59 years, 60 to 69 years, and 70 to 79 years.

The CDVA, DCNVA, and an area of focus metric, such as the distance, intermediate, and near AoF, were all assessed postoperatively and compared among age groups.

Result of the study

The respective CDVAs in the 4 age groups declined with age: −0.18, −0.16, −0.14, and −0.10 logarithm of the minimum angle of resolution (logMAR).

The CDVA was considerably worse in patients in their 70s compared to those younger than 50 years and those in their 50s (p = 0.002 and p = 0.049, respectively), according to Dr. Terauchi.

He reported that the DCNVAs in each of the four age groups followed the same pattern: 0.01, 0.03, 0.03, and 0.08 logMAR.

Patients younger than 50 years old and those in their 60s had significantly poorer DCNVA (p = 0.008 and p = 0.019, respectively).

Finally, compared to patients younger than 50 years and those in their 50s, the near AoF was smaller in the oldest patients (p = 0.040 and p = 0.047, respectively).

The intermediate and distant AoFs in the four groups showed no significant differences. The AoF, on the other hand, showed a "steep" drop in patients over 60 years old.

Reference

Terauchi R, Horiguchi H, Ogawa S, et al. Age-related visual outcomes in eyes with diffractive multifocal intraocular lenses. Eye 2021; https://doi.org/10.1038/s41433-021-01854-x