LayerBio Granted U.S. Patent for OcuRing Drug Delivery Platform

LayerBio Granted U.S. Patent for OcuRing Drug Delivery Platform

December 02, 2021

LayerBio announced that the United States Patent and Trademark Office (USPTO) has issued US Patent No. 11,185,441 for its OcuRing Drug Delivery Platform.

"This patent issuance marks an important milestone for the OcuRing platform and recognition of novelty and uniqueness of our drug delivery technology," Kenneth Mandell, MD, PhD, CEO and Founder of LayerBio, said in a company news release.

"LayerBio will continue to develop our portfolio of patents for the OcuRing platform in order to produce safer, more effective and better-tolerated alternatives to topical eye drops for patients undergoing cataract surgery."

The patent covers a variety of drug product compositions, methods of use, and delivery systems for LayerBio's propriety bioerodible drug delivery rings that release therapeutic medications for use in cataract surgery.

"OcuRing has the potential to transform the standard of care for cataract surgery," Richard Lindstrom, MD, a leading expert in cataract surgery and member of LayerBio's Board of Directors, said in the news release. "By automatically releasing medicine inside the eye after cataract surgery, OcuRing can ensure compliance, improve outcomes and enhance the overall patient experience."

LayerBio's lead product candidate OcuRing-K is a sustained-release nonsteroidal anti-inflammatory drug (NSAID) formulation of ketorolac, an opioid-sparing analgesic with proven efficacy for reducing inflammation and pain associated with cataract surgery.

"OcuRing-K is a game-changer because it provides all of the benefits of an NSAID without the ocular surface side effects," said Eric Donnenfeld, MD, chair of LayerBio's medical advisory board. "By delivering ketorolac directly inside the eye, it maintains a therapeutic plateau and essentially eliminates the risks of surface corneal toxicity associated with NSAID eye drops."

The OcuRing platform can also deliver other ocular drugs, such as corticosteroids, antibiotics, and glaucoma treatments, in addition to NSAIDs. LayerBio will continue to create cutting-edge products to meet unmet medical requirements in cataract surgery and other eye disorders.